Platform

Spica Adventure

2003 · Taito

Arcade · Legacy Mobile Device

Platform · Adventure · Arcade

Spider-Man 2: The Sinister Six

2001 · Torus Games

Game Boy Color

Platform

Spider-Man 3

2004 · Vicarious Visions, Sintax

Game Boy Color · Game Boy Advance

Platform

Spider-Man 3: Invasion of Spider-Slayers

1993 · Bits Studios

Game Boy

Platform

Spider-Man: Battle for New York

2006 · Torus Games

Nintendo DS · Game Boy Advance

Platform

Spider-Man: Mysterio's Menace

2001 · Vicarious Visions

Game Boy Advance · Digiblast

Platform

Spiderbot

1986 · Addictive Games Ltd

Commodore C64/128/MAX · Apple II

Platform · Puzzle

Spiky Harold

1986

Commodore C64/128/MAX · Amstrad CPC · ZX Spectrum · Atari 8-bit · +1

Platform

Spinmaster

1993 · Data East

Wii · Arcade · Neo Geo AES · Zeebo

Platform · Hack and slash/Beat 'em up

Spirits

1987 · Topo Soft

Amstrad CPC · ZX Spectrum · MSX

Platform · Adventure · Puzzle

Spirou: The Robot Invasion

2000 · Planet Interactive Development

Game Boy Color

Platform

Splatterhouse: Wanpaku Graffiti

1989 · Now Production

Nintendo Entertainment System

Platform · Hack and slash/Beat 'em up

SpongeBob SquarePants: Legend of the Lost Spatula

2001 · Vicarious Visions

Game Boy Color

Platform · Adventure

Springer

1982 · Orca

Arcade · Atari 2600 · Atari 8-bit · Commodore VIC-20

Platform · Arcade

Spy Kids 3-D: Game Over

2003

Game Boy Advance

Platform

Spy Kids Challenger

2002 · Game Titan

Game Boy Advance

Platform

Spy's Demise

1982

Commodore C64/128/MAX · Atari 8-bit · Apple II · Texas Instruments TI-99

Platform

Spyro 2: Season of Flame

2002 · Digital Eclipse

Game Boy Advance

Platform

Spyro Orange: The Cortex Conspiracy

2004 · Vicarious Visions

Game Boy Advance

Platform · Adventure

Spyro: Attack of the Rhynocs

2003 · Digital Eclipse

Game Boy Advance

Platform

Spyro: Season of Ice

2001 · Digital Eclipse

Game Boy Advance

Platform

Sqrxz 4: Cold Cash

2014 · Retroguru

Wii · PlayStation · Amiga · Nintendo GameCube · +3

Platform

Sqrxz III

2011 · Retroguru

Wii · Amiga · Nintendo GameCube · Dreamcast · +3

Platform

Squid Jump

2023 · PrimmR

Arduboy

Platform